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. 2021 Jan 22;180(2):239–251. doi: 10.1093/toxsci/kfab005

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Figure 9. — Structural rendition of PAS-B from AHR^b1 showing location of amino acids relevant to described mutants. The structure of the PAS-B domain modeled from AHR^b1 sequence is shown in light blue. A TCDD molecule is shown in the ligand-binding pocket in yellow. Residue 375 (Alanine) is highlighted in purple. The Glycine residue at 368 mutated in the AHR^NG367R model is highlighted in red andlocated in the hairpin loop. The residues changed in AHR^Ter383 as a result of the frame shift mutation are highlighted in dark blue.