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Interference with ST8SIA1 inhibits the promoting effects of MIR4435-2HG on the growth of prostate cancer cells in vivo. (A) Tumor weight. (B) Mouse body weight changes from the 1st to the 20th day. (C) Tumor volume changing from the 1st to the 20th day. (D) The expression of KI67, survivin, MMP2 and MMP9 in tumor tissues was detected by western blot analysis. *P<0.05, **P<0.01 and ***P<0.001 vs. control group; #P<0.05 and ###P<0.001 vs. pcDNA-MIR4435-2HG group.
