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. 2021 Apr 5;2021:6665601. doi: 10.1155/2021/6665601

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Copyright © 2021 Eman A. Ahmed et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Schematic diagram showing the immunomodulatory effect of BM-MSCs+IMC administered concurrently in CFA-induced arthritis. IMC: indomethacin; BM-MSCs: bone marrow-derived mesenchymal stem cells; Th2: T helper 2; DC: dendritic cell; IL-10: interleukin 10; T cell: T lymphocytes; B cell: B lymphocytes; Mono: monocytes; Neut: neutrophils; SM: synovial membrane; iNOS: inducible nitric oxide synthase; TGF-β1: transforming growth factor-beta-1; TNF-α: tumor necrosis factor-alpha; anti-CCP: anticyclic citrullinated peptide antibody; MMP-9: matrix metalloproteinase-9.