Table 2.
The dataset of 66 proteins for pathway enrichment analysis.
| ID | Protein name | Degree | Closeness centrality | Betweenness centrality |
|---|---|---|---|---|
| P42574 | Caspase-3 | 23 | 0.31 | 0.01 |
| Q13547 | Histone deacetylase 1 | 20 | 0.31 | 0.01 |
| P78527 | DNA-dependent protein kinase catalytic subunit | 21 | 0.32 | 0.01 |
| P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 13 | 0.31 | 0.01 |
| P05412 | Transcription factor AP-1 | 16 | 0.33 | 0.01 |
| P23219 | Prostaglandin G/H synthase 1 | 44 | 0.34 | 0.01 |
| Q16665 | Hypoxia-inducible factor 1-alpha | 22 | 0.30 | 0.01 |
| P30305 | M-phase inducer phosphatase 2 | 24 | 0.33 | 0.01 |
| P49336 | Cyclin-dependent kinase 8 | 26 | 0.32 | 0.01 |
| P07900 | Heat shock protein HSP 90-alpha | 41 | 0.37 | 0.02 |
| P50613 | Cyclin-dependent kinase 7 | 13 | 0.32 | 0.01 |
| P04629 | High affinity nerve growth factor receptor | 20 | 0.33 | 0.01 |
| P23458 | Tyrosine-protein kinase JAK1 | 28 | 0.34 | 0.01 |
| P62993 | Growth factor receptor-bound protein 2 | 20 | 0.32 | 0.01 |
| O60674 | Tyrosine-protein kinase JAK2 | 30 | 0.34 | 0.01 |
| Q99558 | Mitogen-activated protein kinase kinase kinase 14 | 26 | 0.33 | 0.01 |
| P42345 | Serine/threonine-protein kinase mTOR | 25 | 0.33 | 0.01 |
| P35354 | Prostaglandin G/H synthase 2 | 51 | 0.34 | 0.01 |
| P09874 | Poly [ADP-ribose] polymerase 1 | 40 | 0.35 | 0.02 |
| P06213 | Insulin receptor | 26 | 0.33 | 0.01 |
| P31749 | RAC-alpha serine/threonine-protein kinase | 22 | 0.33 | 0.01 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | 28 | 0.36 | 0.01 |
| P49841 | Glycogen synthase kinase-3 beta | 31 | 0.35 | 0.01 |
| Q96GD4 | Aurora kinase B | 19 | 0.32 | 0.01 |
| P00918 | Carbonic anhydrase 2 | 76 | 0.37 | 0.01 |
| P18031 | Tyrosine-protein phosphatase nonreceptor type 1 | 53 | 0.35 | 0.01 |
| P22303 | Acetylcholinesterase | 65 | 0.36 | 0.01 |
| P11511 | Aromatase | 83 | 0.36 | 0.02 |
| P11362 | Fibroblast growth factor receptor 1 | 18 | 0.30 | 0.01 |
| P09619 | Platelet-derived growth factor receptor beta | 23 | 0.33 | 0.01 |
| P04049 | RAF protooncogene serine/threonine-protein kinase | 35 | 0.33 | 0.02 |
| O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | 23 | 0.32 | 0.01 |
| O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | 27 | 0.34 | 0.01 |
| O14965 | Aurora kinase A | 29 | 0.34 | 0.01 |
| P24941 | Cyclin-dependent kinase 2 | 41 | 0.34 | 0.01 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | 58 | 0.34 | 0.01 |
| P06493 | Cyclin-dependent kinase 1 | 35 | 0.34 | 0.01 |
| P09917 | Arachidonate 5-lipoxygenase | 55 | 0.36 | 0.01 |
| P04150 | Glucocorticoid receptor | 54 | 0.36 | 0.01 |
| P43405 | Tyrosine-protein kinase SYK | 25 | 0.34 | 0.01 |
| P56817 | Beta-secretase 1 | 36 | 0.36 | 0.01 |
| P0DMS8 | Adenosine receptor A3 | 35 | 0.35 | 0.01 |
| P30542 | Adenosine receptor A1 | 47 | 0.36 | 0.01 |
| Q16539 | Mitogen-activated protein kinase 14 | 38 | 0.37 | 0.01 |
| P45983 | Mitogen-activated protein kinase 8 | 25 | 0.33 | 0.01 |
| Q00987 | E3 ubiquitin-protein ligase Mdm2 | 26 | 0.34 | 0.01 |
| P05067 | Amyloid-beta precursor protein | 29 | 0.34 | 0.02 |
| P00533 | Epidermal growth factor receptor | 57 | 0.37 | 0.03 |
| P32246 | C–C chemokine receptor type 1 | 19 | 0.31 | 0.01 |
| P28482 | Mitogen-activated protein kinase 1 | 29 | 0.34 | 0.01 |
| P08581 | Hepatocyte growth factor receptor | 29 | 0.34 | 0.01 |
| P06401 | Progesterone receptor | 53 | 0.35 | 0.01 |
| P03372 | Estrogen receptor | 66 | 0.34 | 0.02 |
| O43570 | Carbonic anhydrase 12 | 40 | 0.35 | 0.01 |
| P00915 | Carbonic anhydrase 1 | 62 | 0.37 | 0.01 |
| P35968 | Vascular endothelial growth factor receptor 2 | 45 | 0.36 | 0.02 |
| P00519 | Tyrosine-protein kinase ABL1 | 24 | 0.33 | 0.01 |
| P28845 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 67 | 0.37 | 0.01 |
| O00519 | Fatty-acid amide hydrolase 1 | 47 | 0.35 | 0.01 |
| P41594 | Metabotropic glutamate receptor 5 | 34 | 0.36 | 0.01 |
| P10275 | Androgen receptor | 108 | 0.38 | 0.05 |
| P37231 | Peroxisome proliferator-activated receptor gamma | 39 | 0.34 | 0.01 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | 38 | 0.35 | 0.01 |
| Q8NER1 | Transient receptor potential cation channel subfamily V member 1 | 49 | 0.36 | 0.01 |
| P34972 | Cannabinoid receptor 2 | 57 | 0.35 | 0.01 |
| P21554 | Cannabinoid receptor 1 | 40 | 0.36 | 0.01 |