Table 2.

Clinical studies reporting the results of direct pulp capping using Biodentine.

Authors	Type of study	Number of teeth	Follow-up	Age (years)	Success rate∗
Studies investigating pulp exposures in permanent caries-free teeth
Nowicka et al. [55]	RCT	MTA: 11 BD: 11	6 weeks	19-28	BD = 100% MTA = 100%
Nowicka et al. [118]	RCT	BD: 11 MTA: 11 CH: 11 Adhesive: 11	6 weeks	19-32	BD = 100% MTA = 100% CH = 100% Bond = 100%
Studies investigating carious pulp exposures in young permanent teeth with immature roots
Katge and Patil [121]	RCT	MTA: 29 BD: 29	12 months	7-9	BD = 100% MTA = 100%
Brizuela et al. [122]	RCT	CH: 53 MTA: 56 Biodentine: 60	12 months	7-16	BD = 100% CH = 86.36% MTA = 86.36%
Parinyaprom et al. [123]	RCT	MTA: 27 BD: 28	6-54 months	6-18	BD = 96.4% MTA = 92.6%
Studies investigating Carious pulp exposures in permanent teeth with mature roots
Linu et al. [124]	Retrospective	BD: 15 cases MTA: 15 cases	18 months	15-30	BD = 92.3% MTA = 84.6%
Awawdeh et al. [126]	RCT	BD: 34 MTA: 34	36 months	16-51	BD = 91.7% MTA = 96%
Lipski et al. [127]		BD: 112	12–18 months	11–79	BD = 82.6%
Hegde et al. [125]	RCT	BD: 12 MTA: 12	6 months	18-40	MTA = 91.7% BD = 83.3%

^∗At the final follow-up recall. RCT: randomized controlled study. BD: Biodentine.