Table 3.

Regression of baseline parameters and overall survival

Parameter	Univariate Cox regression HR [95%CI]		Multivariate Cox regression HR [95%CI]
PET parameter
Lesion number	1.255 [1.058–1.488]	P = 0.009
PSMA-TV	1.299 [1.081–1.561]	P = 0.005
PSMA-TLU	1.171 [1.003–1.367]	P = 0.046
PSMA-TLQ	1.326 [1.112–1.580]	P = 0.002	1.244 [1.007–1.538]	P = 0.043
Blood parameter
Prostate-specific antigen	1.147 [1.021–1.289]	P = 0.021	0.994 [0.861–1.147]	P = 0.937
Lactate dehydrogenase	1.901 [1.347–2.685]	P < 0.001	1.638 [1.110–2.418]	P = 0.013

All included parameters were log (base2) transformed. HR hazard ratio, CI confidence interval, PSMA-TV PSMA tumor volume, PSMA-TLU PSMA tumor volume multiplied by SUV_mean, PSMA-TLQ PSMA tumor volume divided by SUV_mean