Table 1.

Design of the therapy study including the average tumor volumes and body weights of mice at therapy start

Group	Treatment	Number of mice	Injected activity and molar amount	Tumor volume2 (mm3) (average ± SD)	Body weight (g) (average ± SD)
				Day 0	Day 0
A	Vehicle1	9	-	84 ± 24	23.7 ± 2.7
B	[177Lu]Lu-6R-RedFol-1	6	10 MBq, 0.5 nmol	66 ± 8	24.6 ± 1.2
C	[177Lu]Lu-OxFol-1	6	10 MBq, 0.5 nmol	69 ± 22	24.9 ± 1.2
D	[177Lu]Lu-6R-RedFol-1	6	15 MBq, 0.5 nmol	99 ± 33	20.0 ± 0.83
E	[177Lu]Lu-OxFol-1	6	15 MBq, 0.5 nmol	95 ± 20	20.9 ± 1.23

¹Vehicle: 0.05% BSA in PBS

²No significant differences determined between the tumor volumes measured for each group (p > 0.05);

³Significantly lower body weights compared with mice of groups A, B, and C