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. 2021 Apr 12;11:7937. doi: 10.1038/s41598-021-87199-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CCL11 is expressed in serum and synovial fluids (SFs) from rheumatoid arthritis (RA) patients. (A) The levels of CCL11 in the serum from RA patients (n = 26) were higher than those in the serum from healthy controls (HCs) (n = 28). (B) The levels of CCL11 in SFs from patients with RA (n = 15) were higher than those in SFs from patients with osteoarthritis (OA) (n = 16). The data values are expressed as the mean ± SEM. (C) The CCL11 levels were positively correlated with the levels of TNF-α, CCL2/MCP-1 and CCL3/MIP-1α in SFs of RA patients. *p < 0.05 was significant.