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. 2021 Apr 12;12:2177. doi: 10.1038/s41467-021-22495-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a The dataset of CLP/LMPP/MPP cells. b The dataset of donor BM0828. c The human bone marrow dataset. d The mouse forebrain dataset (half). e The mouse forebrain dataset (half) with 25% dropout rate. f The dataset of mouse prefrontal cortex. For all the datasets, we obtained the latent features from SCALE, Scasat, cisTopic, Cusanovich2018, SnapATAC, and RA3, and then implemented t-SNE for visualization.