Fig. 6. NEIL1 RNA clustering reveals efficiently edited alternative structures.

a NEIL1 variants are clustered by RNAclust from the multiple sequence–structure alignment generated by mlocarna. The editing level of each variant are shown according to the heatmap scale. The sequence and structure corresponding to each RNA ID are listed in Supplementary Data 2. b Consensus secondary structure of selected clusters from a and grouped by editing levels. The gray box (“not base-paired”) indicates that there is at least one variant within the cluster that has a different MFE structure at this position (see examples in Supplementary Fig. 7).