Table 5.
The Cox proportional hazards regression analysis for the survival of NETs in the 6 common sites.
| Site of NETs | Rectum | Lung/Bronchus | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||||
| HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |
| Sex | ||||||||
| Referent: Men | ||||||||
| Women | 0.76 | 0.59–0.97 | 0.78 | 0.61–1.00 | 0.64 | 0.59–0.68 | 0.39 | 0.32–0.46 |
| Age | ||||||||
| Referent: < 40 | ||||||||
| 40 ≤ age < 50 | 1.47 | 0.79–2.76 | 1.49 | 0.79–2.78 | 2.02 | 1.29–3.17 | 1.93 | 1.17–3.20 |
| 50 ≤ age < 60 | 3.58 | 2.07–6.19 | 3.63 | 2.10–6.28 | 2.75 | 1.81–4.18 | 2.15 | 1.34–3.44 |
| 60 ≤ age < 70 | 5.65 | 3.25–9.80 | 5.67 | 3.27–9.85 | 3.2 | 2.13–4.81 | 2.37 | 1.49–3.76 |
| 70 ≤ age | 20.73 | 12.3–35.1 | 20.5 | 12.1–34.7 | 6.57 | 4.41–9.80 | 5.07 | 3.22–7.98 |
| The time period of diagnosis | ||||||||
| Referent: T2 (2004–2009) | ||||||||
| T3 (2010–2015) | 0.77 | 0.59–1.01 | 0.86 | 0.65–1.13 | 1.08 | 0.94–1.23 | 1.02 | 0.88–1.18 |
| Site of NETs | Pancreas | Stomach | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||||
| HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |
| Sex | ||||||||
| Referent: men | ||||||||
| Women | 0.77 | 0.63–0.95 | 0.75 | 0.60–0.92 | 0.44 | 0.34–0.58 | 0.56 | 0.43–0.74 |
| Age | ||||||||
| Referent: < 40 | ||||||||
| 40 ≤ age < 50 | 1.41 | 0.92–2.17 | 1.36 | 0.89–2.08 | 1.01 | 0.31–3.28 | 0.82 | 0.25–2.68 |
| 50 ≤ age < 60 | 1.62 | 1.09–2.41 | 1.59 | 1.07–2.37 | 2.28 | 0.80–6.47 | 2 | 0.70–5.70 |
| 60 ≤ age < 70 | 2.31 | 1.56–3.42 | 2.28 | 1.54–3.37 | 4.85 | 1.76–13.4 | 4.05 | 1.47–11.21 |
| 70 ≤ age | 3.92 | 2.66–5.77 | 3.87 | 2.63–5.70 | 10.01 | 3.71–27.0 | 7.79 | 2.87–21.20 |
| The time period of diagnosis | ||||||||
| Referent: T2 (2004–2009) | ||||||||
| T3 (2010–2015) | 0.55 | 0.43–1.69 | 0.52 | 0.41–0.66 | 1 | 0.76–1.30 | 1.03 | 0.79–1.35 |
| Site of NETs | Colon | Small intestine | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | |||||
| HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |
| Sex | ||||||||
| Referent: men | ||||||||
| Women | 1.03 | 0.79–1.35 | 0.89 | 0.68–1.18 | 0.72 | 0.50–1.03 | 0.66 | 0.45–0.95 |
| Age | ||||||||
| Referent: < 40 | ||||||||
| 40 ≤ age < 50 | 1.75 | 0.85–3.64 | 1.76 | 0.85–3.66 | 1.08 | 0.34–3.39 | 1.12 | 0.36–3.53 |
| 50 ≤ age < 60 | 2.66 | 1.34–5.26 | 2.66 | 1.34–5.27 | 1.81 | 0.63–5.20 | 1.84 | 0.64–5.30 |
| 60 ≤ age < 70 | 2.58 | 1.30–5.09 | 2.57 | 1.30–5.09 | 3.08 | 1.09–8.68 | 3 | 1.06–8.44 |
| 70 ≤ age | 5.07 | 2.63–9.76 | 5.18 | 2.69–9.99 | 4.45 | 1.61–12.3 | 4.74 | 1.71–13.17 |
| The time period of diagnosis | ||||||||
| Referent: T2 (2004–2009) | ||||||||
| T3 (2010–2015) | 0.9 | 0.67–1.20 | 0.98 | 0.73–1.31 | 0.75 | 0.53–1.07 | 0.92 | 0.64–1.32 |