Fig. 6. The functional response of KIR2DL2+S2− and KIR2DL3 NK cells.
a Flow cytometry profile from one donor demonstrating gating strategy using 1F12 antibody. b Normalised responses of the gated populations following coculture either wild-type 221 cells or 221 cells transfected with HLA-C*03:04, -C*07:02, -C*12:03 or -C*16:01 is shown. Data are pooled from eight to ten donors from two experiments. Each symbol represents an individual donor and bars depict mean ± SEM values.