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. 2021 Apr 12;11:7944. doi: 10.1038/s41598-021-86754-6

Table 2.

The association between THRα1 expression and clinicopathological characteristics of NSCLC (SCC) cases (No = 48).

Clinicopathological characteristics THRα expression p value
Low (%) Intermediate (%) High (%)
Age
 ≤ 55 2 (16.7) 4 (33.3) 6 (50) 0.232
 > 55 2 (5.6) 8 (22.2) 26 (72.2)
Gender
Male 4 (10.5) 9 (23.7) 25 (65.8) 0.742
Female 0 (0) 3 (30) 7 (70)
Tumor grade
GI 3 (50) 0 (0) 3 (50) 0.011*
GII 1 (4.3) 8 (34.8) 14 (60.9)
GIII 0 (0) 4 (21.1) 15 (78.9)
T stage
T1 2 (50) 0 (0) 2 (50) 0.001*
T2 2 (6.7) 12 (40) 16 (53.3)
T3 0 (0) 0 (0) 14 (100)
N stage
N0 2 (9.5) 9 (42.9) 10 (47.6) 0.007*
N1 2 (15.4) 3 (23.1) 8 (61.5)
N2 0 (0) 0 (0) 14 (100)
Metastasis
M0 4 (10.8) 12 (32.4) 21 (56.8) 0.017*
M1 0 (0) 0 (0) 11 (100)
TNM stage
Stage I 2 (13.3) 8 (53.3) 5 (33.3) 0.003*
Stage II 2 (13.3) 4 (26.7) 9 (60)
Stage III 0 (0) 0 (0) 7 (100)
Stage IV 0 (0) 0 (0) 11 (100)
Overall survival
Censored 3 (23.1) 6 (46.2) 4 (30.8) 0.003*
Event 1 (2.9) 6 (17.1) 28 (80)

Test of significance: Chi-square and Fisher exact tests.

p-value < 0.05 is considered significant.