Table 1.

List of lung cancer samples used for this study.

Case	Sample number	Sex	Age	Lung cancer type	Subtype	Stage	Sample type	Organoid formation	Tumoroid formation	Driver oncogene	Passage number
1	L1	M	80	Small cell carcinoma		pStage IA3	Surgical specimen	◯	X		N/A
2	L2	M	76	Adenocarcinoma		pStage IIIA	Surgical specimen	◯	X		N/A
3	L3	M	79	Adenocarcinoma	Acinar	pStage IA2	Surgical specimen	◯	X		N/A
4	L4	F	56	Adenocarcinoma	Acinar	pStage IVA	Surgical specimen	◯	X	EGFR (Exon 18 G719S)	N/A
5	L5	M	73	Adenocarcinoma	Solid	pStage IA2	Surgical specimen	◯	◎		More than 22 months, passage >92
6	L6	F	77	Adenocarcinoma	Mucinous	pStage IB	Surgical specimen	◯	X		N/A
7	L7	M	76	Squamous cell carcinoma	Poor	pStage IIB	Surgical specimen	◯	X		N/A
8	L8	F	75	Adenocarcinoma		pStage IA3	Surgical specimen	◯	X		N/A
9	L9	M	79	Adenocarcinoma	Papillary	pStage IA2	Surgical specimen	◯	X		N/A
10	L10	F	82	Adenocarcinoma		cStage IVA	Pleural effusion	X	X		N/A
11	L11	M	75	Adenocarcinoma	Papillary	pStage IIA	Surgical specimen	◯	X	EGFR (Exon 21 L858R)	N/A
12	L12	M	69	Adenocarcinoma	Lepidic	pStage IA2	Surgical specimen	◯	X	EGFR (Exon 21 L858R)	N/A
13	L13	F	70	Adenocarcinoma		pStage IIA	Surgical specimen	◯	X	EGFR (Exon 21 L858R)	N/A
14	L14	M	83	Adenocarcinoma	Solid	pStage IB	Surgical specimen	◯	X		N/A
15	L15	M	62	Adenocarcinoma		pStage IA1	Surgical specimen	◯	X	EGFR (Exon 18 G719A)	N/A
16	L16	M	77	Squamous cell carcinoma	Moderate	pStage IA2	Surgical specimen	◯	X		N/A
17	L17	M	69	Adenocarcinoma	Lepidic	pStage IA2	Surgical specimen	◯	X	EGFR (Exon 21 L858R)	N/A
18	L18	M	75	Adenocarcinoma	Solid	pStage IA3	Surgical specimen	◯	X	EGFR (Exon 19 del)	N/A
19	L19	F	65	Adenocarcinoma	Acinar	pStage IIIA	Surgical specimen	◯	◎		More than 22 months, passage >86
20	L20	M	81	Squamous cell carcinoma		pStage IB	Surgical specimen	◯	X		N/A
21	L21	F	70	Adenocarcinoma	Mucinous	pStage IA2	Surgical specimen	◯	X		N/A
22	L23	M	77	Adenocarcinoma		pStage IA2	Surgical specimen	◯	X		N/A
23	L24	M	69	Adenocarcinoma	Acinar	pStage IA2	Surgical specimen	◯	X	EGFR (Exon 18 G719A, S720Y)	N/A
24	L25	F	56	Adenocarcinoma in situ		pStage 0	Surgical specimen	◯	X	EGFR (Exon 18 G719S)	N/A
25	L26	F	70	Adenocarcinoma	Lepidic	pStage IA1	Surgical specimen	◯	X		N/A
26	L27	M	58	Adenocarcinoma	Mucinous	pStage IIIA	Surgical specimen	◯	X		N/A
27	L28	M	52	Adenocarcinoma	Acinar	pStage IIIA	Surgical specimen	◯	X		N/A
28	L29	F	74	Pleomorphic carcinoma		pStage IB	Surgical specimen	◯	X		N/A
29	L30	M	71	Squamous cell carcinoma	Moderate	pStage IIA	Surgical specimen	◯	X		N/A
30	L31	M	84	Adenocarcinoma	Papillary	pStage IA1	Surgical specimen	X	X		N/A
31	L32	F	72	Adenocarcinoma	Lepidic	pStage IA1	Surgical specimen	◯	X		N/A
32	L33	F	50	Adenocarcinoma	Lepidic	pStage IA2	Surgical specimen	◯	X		N/A
33	L34	M	77	Squamous cell carcinoma		pStage IIIA	Surgical specimen	◯	X		N/A
34	L35	M	70	Small cell carcinoma		pStage IB	Surgical specimen	X	X		N/A
35	L37	M	86	Pleomorphic carcinoma		pStage IIB	Surgical specimen	X	X	EGFR (Exon 19 del)	N/A
36	L38	F	71	Adenocarcinoma	Lepidic	pStage IA1	Surgical specimen	X	X		N/A
37	L39	F	77	Squamous cell carcinoma		pStage IIA	Surgical specimen	◯	X		N/A
38	L40	F	86	Adenocarcinoma		pStage IIIA	Surgical specimen	X	X		N/A
39	L41	M	70	Adenocarcinoma		T2aNxMx	Surgical specimen	X	X		N/A
40	L42	M	77	Squamous cell carcinoma		pStage IIA	Surgical specimen	◯	X		N/A
41	L43	F	73	Adenocarcinoma		pStage IVB	Pleural effusion	◯	◎	EGFR (Exon 20 T790M loss, Exon 21 L858R)	>13 months, passage >36