Table 1.

Local ancestry estimates in individuals of European ancestry for ancestral populations AFR, EAS and EUR.

Ancestral population	Non-risk vs risk allele carriers			Non-risk allele carriers: controls vs cases
	Dosage	Difference	P value	dosage	difference	P value
AFR	0.470/0.213	0.257	<1.00E−04	0.452/0.600	−0.148	1.20E−03
EAS	0.641/1.344	−0.703	<1.00E−04	0.668/0.452	0.216	<1.00E−04
EUR	0.889/0.443	0.446	<1.00E−04	0.881/0.948	−0.067	8.31E−02
AFR–EAS	−0.154/−0.726	0.573	<1.00E−04	−0.193/0.141	−0.334	<1.00E−04
AFR–EUR	−0.308/−0.351	0.043	3.40E−01	−0.322/−0.224	−0.098	5.77E−02
EAS–EUR	−0.162/0.504	−0.666	<1.00E−04	−0.138/−0.353	0.216	9.00E−04

Dosage means for single ancestral populations and normed differences for two populations were compared between risk (N = 45) and non-risk allele (N = 956) carriers as well as between controls (N = 838) and neutropenia cases (N = 118) not carrying the risk allele. P values were determined by permutation tests (N = 10,000). Significant results are in bold.