Table 2.
Daily first week conventional coagulation and biochemical tests.
| Laboratory test, median [IQR*] | Overall (n = 221) | VA ECMO (n = 76) | VV ECMO (n = 145) | P value |
|---|---|---|---|---|
| Mean bilirubin, (μmol) | 11.0 [7.0, 27.5] | 26.0 [13.0, 54.0] | 9.00 [6.00, 17.1] | 0.026 |
| Mean lactate, (mmol/L) | 1.4 [1.1, 2.00] | 2.2 [1.2, 5.3] | 1.25 [1.00, 1.6] | < 0.001 |
| Mean lactate dehydrogenase, (units/L) | 496.0 [294.0, 855.8] | 879.5 [478.3, 2301.8] | 427.50 [292.5, 627.5] | 0.021 |
| Mean hemoglobin, (g/L) | 87.0 [79.5, 98.0] | 88.0 [80.5, 102.5] | 86.50 [79.5, 97.00] | 0.548 |
| Mean platelet count, (109/L) | 162.5 [87.3, 222.0] | 97.0 [71.0, 146.0] | 192.00 [134.0, 241.0] | 0.161 |
| Mean activated partial thromboplastin time, (s) | 59.0 [49.0, 70.8] | 59.5 [47.0, 79.0] | 58.50 [49.5, 68.0] | 0.119 |
| Mean international normalised ratio | 1.3 [1.1, 1.6] | 1.8 [1.3, 2.3] | 1.20 [1.10, 1.30] | < 0.001 |
| Mean d-dimer, (mg/L) | 2.2 [1.1, 6.8] | 7.0 [1.8, 10.0] | 1.59 [0.96, 4.04] | 0.027 |
| Mean fibrinogen, (g/L) | 4.8 [3.1, 6.4] | 2.6 [1.9, 4.4] | 5.60 [4.28, 7.00] | < 0.001 |
| Mean anti-Xa, (IU!/mL) | 0.2 [0.1, 0.4] | 0.1 [0.00, 0.2] | 0.27 [0.11, 0.43] | 0.017 |
| Antithrombin III, (%) | 68.0 [48.3, 85.3] | 42.0 [33.5, 55.0] | 78.5 [59.0, 90.3] | < 0.001 |
| %vWF antigen, (%) | 414.0 [344.0, 485.0] | 420.5 [336.0, 490.0] | 405.0 [353.0, 474.0] | 0.271 |
| vWF activity, (%) | 239.0 [188.0, 342.5] | 219.00 [195.5, 308.5] | 259.0 [187.5, 347.5] | 0.760 |
| vWF ratio | 0.6 [0.5, 0.7] | 0.60 [0.56, 0.70] | 0.6 [0.5, 0.8] | 0.972 |