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. 2021 Feb 9;36(4):916–922. doi: 10.1007/s11606-020-06423-8

Table 2.

Health Literacy Scores at Baseline and Change in Scores from Baseline at Each Follow-up, Overall, and by Age Group

Health literacy assessment (range) Baseline (n = 656) Change at first follow-up§ (n = 615) Change at second follow-up|| (n = 492) Change at final follow-up (n = 383)
TOFHLA* (0–100) 77.7 (15.3) − 0.4 (8.2) − 0.9 (9.5)** − 1.8 (8.7) ‡‡
55–59 78.5 (15.1) 0.1 (8.2) − 0.5 (8.7) − 2.1 (8.5) ††
60–64 78.0 (15.4) 0.3 (8.2) − 0.2 (8.6) − 1.8 (7.8)**
65–74 76.6 (15.5) − 1.4 (8.2)** − 1.8 (11.0)** − 1.7 (9.6)**
p value# 0.40 0.07 0.31 0.93
NVS (0–6) 3.2 (2.1) − 0.1 (1.4) − 0.1 (1.6) − 0.2 (1.4)**
55–59 3.3 (2.2) − 0.1 (1.4) − 0.1 (1.4) 0.1 (1.3)
60–64 3.3 (2.1) − 0.1 (1.4) − 0.1 (1.6) − 0.2 (1.5)
65–74 2.9 (1.9) − 0.1 (1.4) − 0.05 (1.6) − 0.4 (1.6) ††
p value# 0.12 0.98 0.97 0.04
REALM (0–66) 59.9 (11.0) 0.2 (3.3) 0.3 (2.5) †† 0.1 (2.1)
55–59 59.4 (12.2) 0.5 (4.0) − 0.1 (2.4) − 0.1 (1.9)
60–64 60.4 (10.2) − 0.1 (1.9) 0.5 (2.0) †† 0.01 (2.1)
65–74 60.0 (10.5) 0.2 (3.5) 0.6 (3.0)** 0.4 (2.2)**
p value# 0.63 0.26 0.05 0.08

*TOFHLA, Test of Functional Health Literacy in Adults

NVS, Newest Vital Sign

REALM, Rapid Estimate of Adult Literacy in Medicine

Values represent mean (SD)

§Average time 3.2 (0.5) years

||Average time 6.0 (0.6) years

¶Average time 8.6 (0.5) years

#p value represents comparisons of scores by age group using ANOVA

Paired t tests were used to assess change in performance between baseline and each follow-up interview overall and within age groups

**p < 0.05

††p < 0.01

‡‡p < 0.001