TABLE 2.
Correlations between PNI and toxicity assessment.
| Parameters | PNI (n = 477) |
||||
| N | Low PNI (n = 167) | High PNI (n = 310) | χ2 | P value | |
| Decreased appetite | 0.898 | 0.343 | |||
| No | 70 (14.68%) | 28 (16.77%) | 42 (13.55%) | ||
| Yes | 407 (85.32%) | 139 (83.23%) | 268 (86.45%) | ||
| Nausea | 1.136 | 0.286 | |||
| No | 59 (12.37%) | 17 (10.18%) | 42 (13.55%) | ||
| Yes | 418 (87.63%) | 150 (89.82%) | 268 (86.45%) | ||
| Vomiting | 2.315 | 0.128 | |||
| No | 234 (49.06%) | 74 (44.31%) | 160 (51.61%) | ||
| Yes | 243 (50.94%) | 93 (55.69%) | 150 (48.39%) | ||
| Diarrhea | 0.299 | 0.584 | |||
| No | 444 (93.08%) | 154 (92.22%) | 290 (93.55%) | ||
| Yes | 33 (6.92%) | 13 (7.78%) | 20 (6.45%) | ||
| Mouth ulcers | 1.424 | 0.233 | |||
| No | 463 (97.07%) | 160 (95.81%) | 303 (97.74%) | ||
| Yes | 14 (2.93%) | 7 (4.19%) | 7 (2.26%) | ||
| Alopecia | 0.003 | 0.958 | |||
| No | 222 (46.54%) | 78 (46.71%) | 144 (46.45%) | ||
| Yes | 255 (53.46%) | 89 (53.29%) | 166 (53.55%) | ||
| Peripheral neurotoxicity | 0.132 | 0.717 | |||
| No | 390 (81.76%) | 138 (82.63%) | 252 (81.29%) | ||
| Yes | 87 (18.24%) | 29 (17.37%) | 58 (18.71%) | ||
| Anemia | 7.064 | 0.029 | |||
| Grade 0 | 257 (53.88%) | 77 (46.10%) | 180 (58.06%) | ||
| Grades 1–2 | 215 (45.07%) | 87 (52.10%) | 128 (41.29%) | ||
| Grades 3–4 | 5 (1.05%) | 3 (1.80%) | 2 (0.65%) | ||
| Leukopenia | 13.570 | 0.001 | |||
| Grade 0 | 138 (28.93%) | 31 (18.56%) | 107 (34.52%) | ||
| Grades 1–2 | 233 (48.85%) | 95 (56.89%) | 138 (44.52%) | ||
| Grades 3–4 | 106 (22.22%) | 41 (24.55%) | 65 (20.96%) | ||
| Neutropenia | 5.679 | 0.059 | |||
| Grade 0 | 143 (29.98%) | 39 (23.35%) | 104 (33.55%) | ||
| Grades 1–2 | 179 (37.53%) | 71 (42.51%) | 108 (34.84%) | ||
| Grades 3–4 | 155 (32.49%) | 57 (34.13%) | 98 (31.61%) | ||
| Thrombocytopenia | 0.511 | 0.774 | |||
| Grade 0 | 372 (77.99%) | 128 (76.65%) | 244 (78.71%) | ||
| Grades 1–2 | 98 (20.55%) | 37 (22.15%) | 61 (19.68%) | ||
| Grades 3–4 | 7 (1.46%) | 2 (1.20%) | 5 (1.61%) | ||
| Gastrointestinal reaction | 2.347 | 0.309 | |||
| Grade 0 | 38 (7.97%) | 9 (5.39%) | 29 (9.35%) | ||
| Grades 1–2 | 433 (90.78%) | 156 (93.41%) | 277 (89.35%) | ||
| Grades 3–4 | 6 (1.25%) | 2 (1.20%) | 4 (1.30%) | ||
| Myelosuppression | 7.066 | 0.029 | |||
| Grade 0 | 90 (18.87%) | 21 (12.57%) | 69 (22.26%) | ||
| Grades 1–2 | 175 (36.69%) | 63 (37.72%) | 112 (36.13%) | ||
| Grades 3–4 | 212 (44.44%) | 83 (49.71%) | 129 (41.61%) | ||
| Hepatic dysfunction | 0.612 | 0.736 | |||
| Grade 0 | 371 (77.78%) | 129 (77.25%) | 242 (78.07%) | ||
| Grades 1–2 | 105 (22.01%) | 38 (22.75%) | 67 (21.61%) | ||
| Grades 3–4 | 1 (2.10%) | 0 (0.00%) | 1 (0.32%) | ||