Table 3.

Evolution of immunohistochemical parameters over time.

Patient ID	Changes between initial diagnosis and recurrence									Post recurrence survival [months]
	PSMA-positive vessels		CD34-positive vessels		PSMA/CD34ratios		PSMA-positive non-endothelial cells
	amount	score	amount	score	amount	score	intensity	amount	IRS
1	-32%	↔	-65%	↑	↑	↓	↑	↑	↑	22.2
2	-71%	↔	-19%	↑	↓	↓	↑	↔	↑	35.3
3	+63%	↑	-28%	↑	↑	↔	↓	↔	↓	7.5
4	-99%	↓	-92%	↓	↓	↔	↔	↑	↑	5.6
5	-27%	↔	-86%	↔	↑	↔	↔	↔	↔	8.7
6	+125%	↑	+193%	↑	↓	↑	↑	↑	↑	32.4
7	-50%	↓	-65%	↔	↓	↓	↑	↑	↑	12.7
8	-99%	↔	-91%	↓	↓	↑	↓	↑	↔	63.5
9	-51%	↓	n. a.	↓	n. a.	↓	↑	↔	↑	18.4
10	+36%	↑	-32%	↑	↑	↔	↔	↑	↑	12.0
11	-91%	↓	-49%	↔	↓	↓	↔	↑	↑	26.8
12	-100%	↓	-67%	↔	↓	↓	↓	↓	↓	28.3
13	+329%	↑	+218%	↑	↑	↑	↓	↓	↓	3.4
14	-31%	↔	-71%	↓	↑	↓	↑	↑	↑	32.7
15	-92%	↓	-71%	↓	↓	↓	↑	↔	↑	4.5
16	-10%	↔	+47%	↑	↓	↓	↑	↑	↑	18.5

↔, stable; ↑, increase; ↓, decrease; IRS, immunoreactive score; n. a., not available (excluded due to unspecific CD34 staining).