T cells infiltration in iExoSTINGa-treated tumors.A–D, quantitative analyses of flow cytometry measurement of CD45+ (A), CD3+ (B), CD4+, and CD8+ (C) cells in the tumors of the indicated groups. A, Kruskall–Wallis with Dunn's multiple comparison test performed; B and C, one-way ANOVA with Bonferroni's multiple comparison test performed. D and E, quantitative analyses of flow cytometry measurement of CD4+Ki67+ (D) and CD8+Ki67+ (E) cells in the tumors of the indicated groups. D and E, one-way ANOVA with Bonferroni's multiple comparison test performed. The data are presented as the mean ± SEM. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, ∗∗∗∗ p < 0.0001. ns, not significant.