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. 2021 Apr 12;181(6):786–794. doi: 10.1001/jamainternmed.2021.1000

Table 2. Study Outcomes.

Variable No. (%)a P value
Preintervention (n = 113) Postintervention (n = 96)
ICU LOS, median (IQR), d 8.7 (5.7-18.3) 7.4 (5.2-11.5) .02
Multivariable analysis, reduction, % (95% CI)b 24.9 (8.6-38.2) .004
Hospital LOS, median (IQR), d 14.2 (7.4-27.2) 10.7 (6.7-18.1) .01
Multivariable analysis, reduction, % (95% CI)b 28.8 (10.4-43.4) .005
Family meetings 68 (60.2) 92 (95.8) <.001
Day of first meeting, median (IQR) 5.5 (2.0-9.0) 1.0 (1.0-2.0) <.001
Family meeting components
No. 43 59
Description of medical issues 42 (97.7) 59 (100) .24
Discuss prognosis 34 (79.1) 59 (100) <.001
Discuss risk/benefit 15 (34.9) 56 (94.9) <.001
Elicit values and preferences 20 (46.5) 58 (98.3) <.001
Identify improvement markers 9 (20.9) 52 (88.1) <.001
Recommendations for next steps 18 (41.9) 57 (96.6) <.001
Questions 32 (74.4) 59 (100) <.001
Elicit understanding 24 (55.8) 55 (93.2) <.001
ICU procedures
Cardiopulmonary resuscitation in ICU 14 (12.4) 6 (6.3) .32
Vasopressor 62 (54.9) 50 (52.1) .64
Treatment time, median (IQR), d 6.0 (3.0-11.3) 4.0 (3.0-6.5) NA
Noninvasive ventilation 17 (15.0) 13 (13.5) .76
Mechanical ventilation 97 (85.8) 70 (72.9) .02
Treatment time, median (IQR), d 8.0 (5.0-17.5) 7.0 (5.0-12.0) NA
Renal replacement therapy 34 (30.1) 19 (19.8) .09
Thoracentesis 5 (4.4) 3 (3.1) .39
Paracentesis 9 (8.0) 4 (4.2) .53
Lumbar puncture 5 (4.4) 0 .11
Gastrointestinal endoscopy 9 (8.0) 7 (7.3) .59
Bronchoscopy 28 (24.8) 10 (10.4) .03
Central venous catheter 81 (71.7) 38 (40.0) <.001
Do-not-resuscitate order
Present on ICU admission 63 (55.8) 55 (57.3) .82
Present any time during hospitalization 80 (70.8) 86 (89.6) <.001
ICU mortality 51 (45.1) 39 (40.6) .51
Hospital mortality 66 (58.4) 56 (58.3) .99
Hospital disposition of survivors
Hospice 10 (8.9) 11 (11.5) .13
Skilled nursing facility 30 (26.6) 18 (18.8)
Home 7 (6.2) 11 (11.5)
Family satisfaction with ICU care (FS-ICU)
No. 36 33 NA
Total score, mean (SD) 83.4 (13.3) 84.8 (6.3) .55
Satisfaction with medical care, mean (SD) 83.1 (13.3) 83.6 (7.2) .86
Satisfaction with decision-making subscale, mean (SD) 83.6 (14.9) 86.2 (8.3) .38

Abbreviations: APACHE II, Acute Physiology and Chronic Health Evaluation II; FS-ICU, Family Satisfaction in the Intensive Care Unit; ICU, intensive care unit; IQR, interquartile range; LOS, length of stay; NA, not applicable.

a

Values are expressed as No. (%) unless otherwise specified.

b

Shown are back-transformed (100 × [1-eβ]) β coefficients for the multivariable linear regression model of log LOS adjusted for age, Charlson Comorbidity Index, APACHE II score, and ICU admission diagnosis and hospital.