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. 2021 Mar 15;7(4):811–825. doi: 10.1021/acsinfecdis.0c00676

Table 1. 72 h IC50 Values of MMV085203-Resistant Clones Generated from in Vitro Evolution.

MMV085203 IC50 (nM) fold shift
3D7 parent 54.9 ± 27  
3D7-1F2 252.0 ± 114.3 5
3D7-1G5 311.6 ± 108.3 6
3D7-2B3 289.6 ± 86.1 5
3D7-3B3 213.9 ± 85.4 4
3D7-3F3 241.8 ± 78.1 4