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. 2021 Mar 15;7(4):811–825. doi: 10.1021/acsinfecdis.0c00676

Table 3. SNVs Obtained from the in Vitro Evolution of a 3D7 Strain of P. falciparum against MMV085203.

gene name description effect 3D7-1F2 3D7-1G5 3D7-2B3 3D7-3B3 3D7-3F3
PF3D7_0221700 Plasmodium exported protein, unknown function D63_G64insPKPSTLNP   x   x  
PF3D7_0312500 major facilitator superfamily related transporter, putative C401Y x       x
PF3D7_0312500 major facilitator superfamily related transporter, putative Q487E     x    
PF3D7_0312500 major facilitator superfamily related transporter, putative S519stop   x      
PF3D7_0312500 major facilitator superfamily related transporter, putative N279frameshift       x  
PF3D7_0718000 dynein heavy chain, putative intronic indel       x  
PF3D7_0812100 conserved protein, unknown function T1326_T1335del x       x
PF3D7_0823000 serine/threonine protein kinase VPS15, putative N830K   x   x  
PF3D7_0918800 dihydrouridine synthase, putative N526D x       x
PF3D7_1227200 potassium channel D1330Y   x      
PF3D7_1233600 asparagine- and aspartate-rich protein 1 D3256_N3262del       x  
PF3D7_1372200 histidine-rich protein III H119_H124del x       x