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. 2021 Apr 2;45(6):88. doi: 10.3892/or.2021.8039

Table I.

Associations between mRNA levels of CREB, EP300, GPX4 and clinicopathological parameters including age, sex and tumor stage.

Sex Tumor stage


mRNA levels Age (years) P-value (Independent-sample Student's t-test) Male Female P-value (χ2 test) I II III IV P-value (Fisher's exact test)
CREB high 65.44 0.152 8 10 0.180 0 7 8 3 <0.001
CREB low 61.39 12 6 8 9 1 0
GPX4 high 65.94 0.072 7 11 0.044 1 6 8 3 <0.001
GPX4 low 60.89 13 5 7 10 1 0
EP300 high 62.11 0.361 10 8 0.999 0 9 6 3 <0.001
EP300 low 64.72 10 8 8 7 3 0

Data were analyzed by independent-sample Student's t-test, Fisher's exact test and χ2 test.