Table II.
Associations between mRNA levels of CREB, EP300, GPX4 and clinicopathological parameters including smoking habit, tumor diameter as well as N factor.
| Smoking habit | Tumor diameter | N factor | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| mRNA levels | Smoking | Non-smoking | P-value (χ2 test) | ≥3 cm | <3 cm | P-value (χ2 test) | N0 | N1 | N2 | N3 | P-value (Fisher's exact test) |
| CREB high | 5 | 13 | 0.725 | 15 | 3 | 0.002 | 3 | 8 | 5 | 2 | 0.001 |
| CREB low | 7 | 11 | 6 | 12 | 12 | 5 | 1 | 0 | |||
| GPX4 high | 6 | 12 | 1 | 15 | 3 | 0.002 | 3 | 8 | 5 | 2 | 0.001 |
| GPX4 low | 6 | 12 | 6 | 12 | 12 | 5 | 1 | 0 | |||
| EP300 high | 4 | 14 | 0.289 | 14 | 4 | 0.018 | 5 | 9 | 3 | 1 | <0.001 |
| EP300 low | 8 | 10 | 7 | 11 | 10 | 4 | 3 | 1 | |||
Data were analyzed by Fisher's exact test and χ2 test.