Table 5.
KEGG pathway of validated target genes of miR-221-3p
| KEGG ID | KEGG term | Count (%) | Gene symbol | p-value |
|---|---|---|---|---|
| hsa00982 | Drug metabolism - cytochrome P450 | 7 | GSTA1, UGT1A7, CYP3A5, FMO2, MAOB, ADH1C, ADH1B | 3.18E-07 |
| hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 6 | GSTA1, UGT1A7, CYP3A5, CYP2F1, ADH1C, ADH1B | 8.10E-06 |
| hsa00830 | Retinol metabolism | 5 | UGT1A, ALDH1A1, CYP3A5, ADH1C, ADH1B | 6.43E-05 |
| hsa05204 | Chemical carcinogenesis | 5 | GSTA1, UGT1A7, CYP3A5, ADH1C, ADH1B | 1.69E-04 |
| hsa00350 | Tyrosine metabolism | 3 | MAOB, ADH1C, ADH1B | 1.54E-03 |
Notes: KEGG: Kyoto Encyclopedia of Genes and Genomes