Table 3.

Univariate and multivariate analysis results of TEAD4 CNV in TCGA-LGG cohort

	OS				DFS
	Univariate		Multivariate		Univariate		Multivariate
	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)
TEAD4 CNV	0.077	1.288 (0.973–1.703)	0.022	1.444 (1.054–1.978)	0.012	1.382 (1.074–1.778)	0.005	1.485 (1.124–1.962)
Age	6.39 × 10−15	1.058 (1.043–1.074)	1.02 × 10−11	1.056 (1.040–1.073)	4.35 × 10−5	1.026 (1.013–1.039)	0.001	1.023 (1.010–1.037)
Grade	1.58 × 10−9	3.340 (2.258–4.940)	6.99 × 10−5	2.264 (1.513–3.386)	0.003	1.608 (1.174–2.202)
IDH mutation	2.22 × 10−22	0.156 (0.108–0.227)			2.54 × 10−21	0.178 (0.124–0.254)	5.19 × 10−11	0.245 (0.161–0.373)
TP53 mutation	0.039	0.690 (0.485–0.982)	2.42 × 10−7	0.294 (0.185–0.468)	0.791	1.042 (0.767–1.417)
ATRX mutation	0.070	0.714 (0.497–1.028)			0.802	1.040 (0.764–1.416)
1p19q co-deletion	1.21 × 10−4	0.411 (0.261–0.646)	3.41 × 10−11	0.166 (0.098–0.282)	4.64 × 10−6	0.408 (0.278–0.599)	0.008	0.557 (0.362–0.856)