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. 2021 Apr 9;9(4):e002224. doi: 10.1136/jitc-2020-002224

Table 1.

Baseline characteristics and best response to the study treatment

Single agent OH2
(n=40)
OH2 with HX008
(n=14)
Median age at entry, years (range) 55 (27–73) 53 (36–64)
Male 30 (75.0%) 10 (71.4%)
Tumor types
 Esophageal cancer 14 3
 Colorectal (including appendix) cancer 12 6
 Gastric cancer 5 5
 Melanoma and other skin cancer 4 0
 Head and neck cancer 2 0
 Cholangiocarcinoma 1 0
 Ovarian cancer 1 0
 Breast cancer 1 0
Prior treatment with anti-PD-1 antibodies 10 (25.0%) 1 (7.1%)
Best response (iRECIST)
 iPR 2 2
 iSD 9 4
 iUPD 22 6

iPR, immune-partial response; iRECIST, immune-Response Evaluation Criteria in Solid Tumors; iSD, immune-stable disease; iUPD, immune-unconfirmed progressive disease; PD-1, programmed cell death protein 1.