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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Cancer Treat Rev. 2020 Sep 22;91:102106. doi: 10.1016/j.ctrv.2020.102106

Figure 2: Tumor heterogeneity and response to treatment.

Figure 2:

A; Pre-treatment PET/CT scan in newly diagnosed lymphoma demonstrates advanced stage disease.

B; Inguinal lymph node biopsy demonstrating low-grade follicular NHL, H&E stain (x40 magnification).

C; Inguinal lymph node biopsy demonstrating low-grade follicular NHL, BCL-2 IHC stain (x60 magnification).

D; Gastric ulcer biopsy demonstrating high grade B-cell lymphoma DLBCL, H&E stain (x60 magnification).

E; End of treatment PET/CT scan demonstrates near complete remission.

F; MRI scan after NHL treatment demonstrates new peri-ventricular white matter lesions suggestive of NHL relapse.