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. 2021 Mar 29;12:621687. doi: 10.3389/fendo.2021.621687

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Copyright © 2021 Patterson, Combs, Taylor, Patterson, Moler and Wastney

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tracer data for a male subject for Sel (⁷⁶Se-Sel) before (PK1, ▯), and after (PK2, ◼) Se supplementation (A), SeMet (⁷⁴Se -SeMet) in plasma for PK1 (∆) and PK2 (▲) (B) and for SeMet (▲) versus Sel (◼) for PK2 showing similar timing of the peaks between the forms (C) for the first 40 h after isotope administration. Symbols are observed values; lines are model-calculated values ( Supplemental Figure 1 ).