Table 5:
Metabolic stability of active enantiomerically pure compounds derived from a human liver microsome assay.
| Compound | T1/2 (min) | Fold Increase (over S-PF-74) |
|---|---|---|
| S-PF-74 | 0.5 | 1.0 |
| S-CX15 | 15.4 | 30.8 |
| S-CX16 | 1.0 | 2.0 |
| S-CX17 | 102.0 | 204 |
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