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. 2021 Mar 30;12:641361. doi: 10.3389/fendo.2021.641361

Figure 1.

Figure 1

Complement activation pathways. Schematic illustration of classical (left panel), lectin (middle panel), and alternative (right panel) pathways of complement activation, showing links between initiator molecules, proteases and C3, C5 convertases. Upward red arrows indicate the complements that are elevated in the second trimester of pregnancy in gestational diabetes (GDM).