Table 3.

Tabulated relative viscosity values at 150 mg/mL as a function of charges on the heavy and light chain variable regions and ${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$. The charges have a unit of e, and ${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$ has a unit of kcal/mol. The constant region of mAb4 was used as a template

		VH_charge							VH_charge
	${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$=0.4	−2	0	2	4	6		${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$=0.5	−2	0	2	4	6
VL_charge	−2	71.4	38.3	24.4	16.1	10.7	VL_charge	−2	104.4	71.9	41.5	25.4	16.1
	0	34.2	19.4	11.7	8.2	6.4		0	60.3	32.3	16.4	9.9	7.3
	2	18.7	11.5	7.3	5.7	5.4		2	30.4	14.7	8.4	6.2	5.8
	4	11.9	6.6	5.4	4.8	4.8		4	16.1	8.0	5.6	5.2	4.9
	6	7.7	5.8	4.9	4.8	4.8		6	10.1	6.1	5.2	4.9	4.7
		VH_charge							VH_charge
	${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$=0.6	−2	0	2	4	6		${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$=0.7	−2	0	2	4	6
VL_charge	−2	127.3	118.4	84.3	46.9	25.2	VL_charge	−2	145.6	151.0	145.2	112.6	64.6
	0	106.1	72.0	30.3	14.2	8.6		0	150.6	141.4	84.9	23.7	12.4
	2	72.6	25.5	10.7	6.8	5.9		2	138.1	66.5	16.4	8.6	6.5
	4	28.8	10.9	6.7	5.4	5.0		4	77.9	17.4	7.8	5.9	5.1
	6	14.4	7.0	5.5	5.0	4.9		6	28.7	8.7	5.8	5.3	5.2
		VH_charge						VH_charge
	${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$=0.8	−2	0	2	4	6		${\mathrm{A}}_{\mathrm{H}}^{\mathrm{v}}$=0.9	−2	0	2	4	6
VL_charge	−2	155.5	168.4	174.9	171.1	142.5	VL_charge	−2	154.4	169.1	175.8	180.8	181.9
	0	167.4	176.0	160.1	71.1	21.3		0	170.7	177.1	183.3	158.0	59.7
	2	172.4	150.4	43.9	11.8	7.4		2	176.6	182.0	136.4	19.4	9.6
	4	162.1	46.3	10.4	6.4	5.5		4	182.8	141.1	17.3	7.4	6.2
	6	92.4	12.7	6.6	5.3	5.2		6	168.6	28.1	7.7	5.6	5.4