Table 2.

Overall comparisons

	Treatment	Sonovue		Sonazoid		Optison		Definity
	Ultrasound Power	low	high	low	high	low	high	low	high
IP	Tumor Volume (vs chemo)	*	****	◌	**	○	****	***	***
	Hemoglobin total (vs chemo)	N/A	○	N/A	◌	N/A	○	N/A	○
	Hemoglobin Average (vs chemo)	N/A	○	N/A	○	N/A	○	N/A	○
	SO2 total (vs chemo)	N/A	◌	N/A	*	N/A	○	N/A	○
	SO2 average (vs chemo)	N/A	○	N/A	◌	N/A	○	N/A	*
	Increase in Tomato Lectin Staining	○	○	●	●	●	●	●	●
IV	Tumor Volume vs Chemo	○	○	*	***	○	*	○	○
	% Vasculature vs Chemo	○	○	**	**	○	◌	○	*

Summary of all changes observed sonoporations treatments vs treatments across high and low ultrasound power and both IP and IV treatment groups including the following parameters: tumor volume, hemoglobin total, hemoglobin average, SO2 total, SO2 average, Tomato Lectin staining and % vasculature. The following symbols for this table N/A, ◌, *, **, ***, ****, ●, ○ indicate p < .15, <.05, <.01, <.005, <.001, qualitative change and no change respectively