. Author manuscript; available in PMC: 2021 Apr 13.

Published in final edited form as: J Thromb Haemost. 2020 Aug 27;18(9):2329–2340. doi: 10.1111/jth.14972

TABLE 2.

CBC analysis in WT and HK^−/− sickle mice

Parameter	AA/WT	AA/HK^−/−	SS/WT	SS/HK^−/−
RBC × 10⁶/µL	9.31 ± 0.19	9.73 ± 0.13	5.79 ± 0.11^***	5.89 ± 0.17^***
MCV	36.56 ± 0.99	38.17 ± 1.27	50.88 ± 0.34^***	51.28 ± 0.59^***
Hemoglobin (g/dL)	9.73 ± 0.26	9.73 ± 0.13	7.11 ± 0.18^***	7.28 ± 0.24^***
Hematocrit (%)	35.27 ± 0.68	37.07 ± 1.07	29.46 ± 0.56^***	30.02 ± 0.94^***
WBC × 10³/µL	15.54 ± 2.21	11.36 ± 0.86	33.22 ± 1.67^****	31.09 ± 2.72^****
Neutrophil × 10³/µL	2.82 ± 0.59	1.27 ± 0.14^*	4.96 ± 0.46^*	4.13 ± 0.59^**
Lymphocyte × 10³/µL	9.16 ± 0.50	8.59 ± 0.73	24.67 ± 1.25^****	26.06 ± 2.06^****
Monocyte × 10³/µL	1.03 ± 0.18	0.53 ± 0.04	1.99 ± 0.18^*	1.94 ± 0.20^*

Abbreviations: CBC, complete blood count; Hgb, hemoglobin; HK, high molecular weight kininogen; MCV, mean corpuscular volume; RBC, red blood cell; WBC, white blood cell; WT, wild type.

P < .05.

^**

P < .01.

^***

P < .001.

^****

P < .0001 vs AA/WT or AA/HK^−/− by two-way analysis of variance.