Association of bacterial genera (prevalence is greater than 20% and mean abundance is greater than 0.1%) with asthma. A, Plot of the Wald’s statistics to indicate associations of bacterial genera and asthma among women (x-axis) and men (y-axis). Each data point represents a bacterial genus. The analysis was performed using the GLM in the DESeq2 package in R. B, Relative abundance of Lactobacillus spp. in normal controls and patients with asthma based on sex. Statistical significance was assessed by Wilcoxon rank-sum test. C, Relative abundance of Haemophilus spp. in normal controls and patients with asthma based on sex. Statistical significance was assessed by Wilcoxon rank-sum test. GLM, generalized linear model; spp., species.