Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Western blot analysis of MLV pseudoparticles carrying the WT, B.1.1.7, or P681H S was conducted using an antibody targeting the SARS-CoV-2 S2 domain (Sino Biological). Band intensity was normalized to the uncleaved band intensity of each pseudoparticle.
| Spike protein | Ratio cleaved S : uncleaved S |
|---|---|
| Wuhan-Hu1 (WT) | 4.5 : 1 |
| B.1.1.7 | 22 : 1 |
| Wuhan-Hu1 (P681H) | 14 :1 |
