REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse anti- FOXJ1	Thermo Fisher Scientific	Cat # 14-9965-82; RRID: AB_1548835
Mouse anti- Mucin 5AC, 45M1	Thermo Fisher Scientific	Cat # MA5-12178; RRID: AB_10978001
Mouse anti- HTII-280	Terrace Biotech	Cat # TB-27AHT2-280; RRID: AB_2832931
Mouse anti- HTI-56	Terrace Biotech	Cat # TB-29AHT1-56; RRID: AB_2847898
Guinea Pig anti- SARS-CoV-2 spike (S) protein	BEI Resources	NR-10361
Rabbit anti- Cleaved caspase-3	Cell Signaling Technology	Cat # 9661; RRID: AB_2341188
Mouse anti- CD31	BioLegend	Cat # 303104; RRID: AB_314330
Mouse anti- CD45	BioLegend	Cat # 304054; RRID: AB_2564154
Mouse anti- CD326	BioLegend	Cat # 324208; RRID: AB_756082
Bacterial and virus strains
SARS-CoV-2, isolate USA-WA1/2020 GenBank: MT020880)	BEI Resources	(NR-52281)
Biological samples
Normal Lung Tissue	International Institute for the Advancement of Medicine (IIAM)	N/A
Chemicals, peptides, and recombinant proteins
Hydroxychloroquine	Selleck Chemicals	Cat # S4430
Remdesivir	Selleck Chemicals	Cat # S8932
IFNB1 stock	Provided by Dr Jay Kolls	N/A
Liberase	Millipore Sigma	Cat # 5401127001
Critical commercial assays
CD31 MicroBead Kit, human	Miltenyi Biotec	Cat # 130-091-935
CD45 MicroBead Kit, human	Miltenyi Biotec 130-	Cat # 130-045-801
Deposited data
Raw and analyzed data	This paper	GEO:GSE160435
Experimental models: cell lines
MRC5 human lung fibroblast cells	ATCC	CCL-171
Oligonucleotides
Primers for SARS-CoV-2 N1 gene (See Table S1)	CDC’s resources for research labs	N/A
Primers for IFN Stimulated genes (See Table S1)	This paper	N/A
Software and algorithms
ImageJ	N/A	https://imagej.nih.gov/ij/
GraphPad Prism 8	GraphPad	RRID:SCR_002798
Other
Pneumacult Ex media	Stem Cell Technologies	Cat #05008
Pneumacult ALI media	Stem Cell Technologies	Cat # 05001