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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: NanoImpact. 2021 Mar 13;22:100309. doi: 10.1016/j.impact.2021.100309

Figure 3. Requirement of STAT6 for HDM-induced mucous cell metaplasia and exacerbation by MWCNTs in mice.

Figure 3.

A) Representative photomicrographs of Alcian blue periodic acid Schiff (AB/PAS) stained lung sections in WT and Stat6KO mice after exposure to vehicle, HDM, MWCNTs or MWCNTs with HDM allergen (Bars = 200 μm). B) Quantification of AB/PAS-positive mucosubstances in the airways of WT and Stat6 KO mice. N=4 to 6 animals per group. *p<0.05 vs. vehicle of same genotype, Student’s t-test. #p< 0.05 between WT and Stat6 KO mice, Mann-Whitney test.