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. 2021 Mar 4;15:1198. doi: 10.3332/ecancer.2021.1198

Table 4. BQDS item frequencies, grouped by factor (N = 479).

Item Current study Herzog et al [11]
N (%) Rank % Rank
Factor 1: Physical and psychological urgent need
1. Cannot go on without areca nut 274 (57) 5 62 5
2. Difficulty in concentration after reducing dose 181 (38) 8 57 10
3. Experienced depression or drowsiness 127 (27) 11 52 11
4. The strong craving after reducing/stopping to chew 291 (61) 3 73 1
5. Spend time to find when not available 276 (58) 4 64 3
6. Travel great distance to find when not available 119 (25) 12 58 9
7. Felt agitated, irritated, or anxious after reducing 172 (36) 9 60 8
Factor 2: Increasing dose
8. Trouble stopping once started chewing 295 (62) 1 67 2
9. Ever chewed non-stop 149 (31) 10 61 7
10. Gradually increased the amount of use after first use 292 (61) 2 64 4
11. Felt the need to increase the amount of use periodically 262 (55) 6 52 12
12. Often chewed betel nut/quid more than expected 193 (40) 7 62 6
Factor 3: Maladaptive use
13. Continue chewing teeth loosen 78 (16) 14 39 14
14. Continue chewing if you had sensitive teeth 80 (17) 13 43 13
15. Continue chewing if experienced mouth ulcers 77 (16) 15 26 15
16. Reduced or given up activities because of chewing 75 (16) 16 17 16