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. 2021 Mar 31;10:e65699. doi: 10.7554/eLife.65699

Figure 3. Key interactions in the THO*•Sub2 complex.

(A) A highly intimate interface involving the Tho2 ‘head’. (B) The Tho2 ‘neck’ is embraced by the two lobes of Hpr1. (C) The Hpr1 exhibits an extended ‘belt’ lining the Tho2 ‘trunk’. (D) The Tex1 beta propeller sits at the center of the Tho2 ‘trunk’. (E) The interface between Tho2 and Sub2-C.

Figure 3.

Figure 3—figure supplement 1. Comparison of the cryo-EM structure and our previous crystal structure of THO•Sub2 at the THO–Sub2 interface.

Figure 3—figure supplement 1.

Cryo-EM structure is colored in blue (Tho2), pink (Sub2-N), and purple (Sub2-C). Crystal structure is colored in light blue (Tho2) and gray (Sub2-N and Sub-C).