Table 1:
Comparison of patient characteristics in terms of tricuspid and bicuspid valve morphology
| Tricuspid valve (n = 3882) | Bicuspid valve (n = 1142) | P-value | |
|---|---|---|---|
| Age (years) | 75 (68–79) | 63 (56–71) | <0.001 |
| Female gender | 1550 (39.9) | 331 (29.0) | <0.001 |
| Smoking (current/past) | 1651 (46.0) | 528 (49.4) | 0.046 |
| COPD | 302 (8.0) | 59 (5.3) | 0.002 |
| NYHA functional class III/IV | 2600 (67.4) | 570 (50.3) | <0.001 |
| Heart failure | 795 (21.4) | 190 (17.3) | 0.003 |
| Diabetes mellitus | 858 (22.6) | 153 (13.5) | <0.001 |
| Atrial fibrillation | 627 (16.5) | 107 (9.5) | <0.001 |
| Endocarditis | 83 (2.1) | 23 (2.0) | 0.80 |
| Preoperative serum creatinine (mg/dl) | 84 (71–101) | 84 (71–96) | 0.075 |
| Previous cardiac surgery | 138 (3.6) | 43 (3.80) | 0.79 |
| Combined CABG/AVR | 1684 (43.4) | 251 (22.0) | <0.001 |
| Mechanical valve | 461 (11.9) | 417 (36.5) | <0.001 |
| Primary aortic insufficiencya | 400 (10.4) | 113 (10.1) | 0.72 |
| 30-Day mortality | 100 (2.6) | 11 (0.96) | 0.001 |
| Follow-up time (years) | 4.5 (2.1–7.3) | 4.9 (2.3–8.2) | <0.001 |
Categorical variables are given as n (%), continuous variables as median (p25–p75). Gender differences were tested with the χ2 test and the Mann–Whitney U-test for categorical and continuous data, respectively.
a
Aortic insufficiency was coded if the primary indication for surgery was aortic insufficiency. If patients also had aortic stenosis, aortic stenosis was the main diagnosis.
AVR: aortic valve replacement; CABG: coronary artery bypass grafting; COPD: chronic obstructive pulmonary disease, NYHA: New York Heart Association.