Table 3. Pooled estimates of detection rates with heterogeneity of screening colonoscopy studies.
Outcome | Reported by N studies | Pooled estimate (%)* | 95 % CI | Heterogeneity (I2) |
SDR | 16 | 2.5 % | 1.8 %–3.4 % | 98.66 % |
SDR for prospective studies | 7 | 2.3 % | 1.5 %–3.6 % | 94.19 % |
SDR for large studies (n > 1000) | 13 | 2.4 % | 1.7 %–3.4 % | 98.89 % |
SDR for prospective large studies | 4 | 2 % | 1.1 %–3.3 % | 95.82 % |
PSPDR | 12 | 10 % | 8.5 %–11.8 % | 98.17 % |
PSPDR for prospective studies | 4 | 11 % | 9.6 %–12.7 % | 82.01 % |
PSPDR for large studies (n > 1000) | 11 | 10 % | 8.4 %–11.9 % | 98.34 % |
PSPDR for prospective large studies | 3 | 11.2 % | 9.3 %–13.5 % | 87.95 % |
Any Serrated polyp detection rate | 10 | 22 % | 14.9 %–31.2 % | 99.7 % |
Large serrated polyp detection rate | 6 | 1.6 % | 1.2 %–2.2 % | 89.87 % |
Large SSL detection rate | 4 | 1.1 % | 0.5 %–2.2 % | 95.53 % |
Proximal SSL detection rate | 5 | 1.6 % | 1.1 %–2.4 % | 93.59 % |
SSL with dysplasia detection rate | 7 | 0.8 % | 0.4 %–1.6 % | 92.78 % |
TSA detection rate | 6 | 0.2 % | 0.1 %–0.6 % | 82.64 % |
Synchronous Advanced ADR | 16 | 19.1 % | 15.6 %–23.1 % | 99.63 % |
Clinically significant serrated polyp detection rate | 4 | 6.3 % | 4.6 %–8.5 % | 98.4 % |
*For all outcomes, P < 0.01; SSL, sessile serrated lesion; SDR, SSL detection rate; PSPDR, proximal serrated polyp detection rate; ADR, adenoma detection rate; TSA, traditional serrated adenoma.