Table 4.
Effect of each EPI and AZM on the virulence factors production in the 14 P. aeruginosa isolates (with affected QS signals in presence of EPI)
| Virulence factors | Number of isolates (n=14) | ||||
|---|---|---|---|---|---|
| In absence of AZM & EPI | In presence of AZM | In presence of EPI | ***Significance | ||
| Biofilm | Strong | 10 (71.4%) | 3 (21.4%) | 3 (21.4%) | ªp=0.132 |
| Moderate | 3 (21.4%) | 4 (28.6%) | 8 (57.1%) | ||
| **Significance | ------ | ªp=0.004 | ªp=0.007 | ||
| Pyocyanin | Positive | 12 (85.7%) | 3 (21.4%) | 0 (0%) | ªªp=0.867 |
| **Significance | ------ | ªªp=0.004 | ªªp=0.001 | ||
| Rhamnolipid | Positive | 12 (85.7%) | 1 (7.1%) | 5 (35.7%) | ªªp=0.472 |
| **Significance | ------ | ªªp=0.001 | ªªp=0.004 | ||
| Protease | Positive | 14 (100%) | 1(7.1%) | 6 (42.9%) | ªp=0.225 |
| Decreased* | 0 | 10 (71.4%) | 5 (35.7%) | ||
| **Significance | ----- | ªp=0.317 | ªp=0.317 | ||
*
Reduction in diameter of halo zone
**
tests for presence and absence of AZM or EPI
***
tests for presence AZM and EPI.
ª
marginal test of homogeneity. results≤ 0.05 are significant.
ªª
Cochrane's Q test. results≤ 0.05 are significant