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. 2021 Apr 9;14:2433–2448. doi: 10.2147/OTT.S296373

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© 2021 Wang et al.

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Validation of the hub genes in Tumor and Immune System Interaction Database. (A) and (C–F) represent heat maps of the correlation between hub genes and immune cells, chemokines, receptors, immune-inhibitory factors, and immune-stimulatory factors, respectively. (B) shows the protein–protein interaction network of the immune microenvironment. Green represents hub genes, red represents chemokines, purple represents receptors, yellow represents immune-inhibitory factors, and blue represents immune-stimulatory factors.