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. 2020 Dec 11;32(5):865–871. doi: 10.1007/s00198-020-05766-6

Table 2.

Univariate correlations between hemoglobin, neutrophils, lymphocytes, platelets, and total hip BMD and selected variables in the study cohort MrOS Gothenburg (n = 1005)

Hemoglobin Neutrophils Lymphocytes* Platelets Total hip BMD
r P r P r P r P r P
Age − 0.12 < 0.001 − 0.01 0.689 0.06 0.055 − 0.06 0.078 − 0.06 0.039
BMI 0.19 < 0.001 0.02 0.462 − 0.09 0.007 0.02 0.46 0.45 < 0.001
Total body BMD 0.06 0.056 − 0.09 0.006 − 0.04 0.171 − 0.08 0.012 0.73 < 0.001
Total hip BMD^ 0.16 < 0.001 −0.08 0.010 −0.05 0.150 −0.11 0.003 NA NA
LS L1–4 BMD^ 0.06 0.069 − 0.03 0.292 − 0.00 0.904 − 0.06 0.041 0.66 < 0.001
Hemoglobin NA NA 0.08 0.018 0.13 < 0.001 − 0.01 0.686 0.16 < 0.001
Neutrophils 0.08 0.018 NA NA 0.06 0.048 0.32 < 0.001 − 0.08 0.010
Lymphocytes* 0.13 < 0.001 0.06 0.048 NA NA 0.11 < 0.001 0.02 0.441
Platelets − 0.01 0.686 0.32 < 0.001 0.11 < 0.001 NA NA − 0.11 0.003
Hand-grip strength 0.15 < 0.001 − 0.07 0.02 0.01 0.857 0.00 0.898 0.16 < 0.001
Walking speed test 0.06 0.080 − 0.17 < 0.001 0.00 0.161 0.01 0.629 0.00 0.904
Current smoker 0.02 0.483 0.23 < 0.001 0.02 0.563 0.02 0.606 − 0.11 < 0.001
Osteocalcin* − 0.13 < 0.001 − 0.01 0.751 − 0.11 < 0.001 0.06 0.068 − 0.31 < 0.001
ALP* − 0.01 0.743 0.15 < 0.001 − 0.02 0.521 0.05 0.087 − 0.10 0.003
P1NP* − 0.06 0.075 − 0.02 0.528 − 0.08 0.009 0.00 0.918 − 0.18 < 0.001
eGFR 0.13 < 0.001 − 0.17 < 0.001 0.03 0.275 − 0.02 0.589 − 0.01 0.810
25(OH)D** − 0.02 0.468 − 0.01 0.801 0.02 0.628 0.02 0.625 0.04 0.219
Estradiol 0.26 < 0.001 − 0.00 0.983 0.017 0.601 − 0.03 0.401 0.14 < 0.001
CRP* − 0.11 < 0.001 0.318 < 0.001 − 0.06 0.032 0.15 < 0.001 0.02 0.616
Phosphate − 0.12 < 0.001 0.08 0.010 0.08 0.016 0.07 0.022 − 0.05 0.100
PTH* − 0.04 0.235 − 0.02 0.573 − 0.05 0.096 − 0.07 0.020 − 0.08 0.008
Serotonin − 0.00 0.911 0.10 0.001 0.12 < 0.001 0.27 < 0.001 − 0.08 0.010
EPO* − 0.32 < 0.001 − 0.10 0.001 − 0.17 0.003 − 0.18 < 0.001 0.11 < 0.001
Iron deficiency − 0.18 < 0.001 0.19 < 0.001 − 0.02 0.494 0.14 < 0.001 0.01 0.734
iFGF23* − 0.09 0.004 0.07 0.020 − 0.06 0.063 − 0.08 0.018 0.09 0.007
Prevalent cancer − 0.12 < 0.001 0.01 0.750 0.04 0.227 0.02 0.481 − 0.01 0.799
Physical activity − 0.02 0.585 − 0.14 < 0.001 0.04 0.190 − 0.00 0.881 0.01 0.667
Comorbidity index − 0.03 0.416 0.19 < 0.001 0.05 0.100 − 0.05 0.094 0.12 < 0.001

Comorbidity index: diabetes mellitus, stroke, myocardial infarction, hypertension, chronic bronchitis. LS lumbar spine

*Log variable; **Seasonal 25(OH)D; ^Standardized