Table 3.
Characteristics of tumors and patients who showed recurrence
| Age/Gender | Baseline cTN | nCRT | Post nCRT ycTN | Post LE ypT | TRG | Margin | Completion TME surgery | TTLR (months) | Treatment for local recurrence | TTDR | Site of Distant recurrence |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 53/M | T3N+ | Capecitabine + 50.4 Gy | ycT1N0 | 2 | 3 | Negative | Required/Refused | 49 | Local re-excision | 10 | Liver |
| 74/M | T3N+ | Capecitabine + oxaliplatin + 50.4 Gy | ycT2N0 | 2 | 2 | Positive | Required/Refused | 32 | LAR + IORT | 61 | Lung |
| 61/M | T3N+ | Capecitabine + 55 Gy | ycT0N0 | 3 | 3 | Negative | Required/Refused | 41 | APR | 53 | Liver, lung |
| 79/F | T2N+ | Capecitabine + 50.4 Gy | ycT0N0 | 0 | 1 | Negative | Not required | 44 | Refused | None | None |
| 72/F | T3N+ | Capecitabine +oxaliplatin +50.4 Gy | ycT2N+ | 0 | 1 | Negative | Not required | 41 | CRT | 45 | Adrenal gland |
| 63/M | T2N+ | Capecitabine +55 Gy | ycT1N0 | 0 | 1 | Negative | Not required | None | None | 32 | Liver, lung |
| 54/F | T2N+ | Capecitabine +oxaliplatin +50.4 Gy | ycT2N0 | 1 | 4 | Negative | Performed | None | None | 33 | Lung |
| 54/M | T2N0 | Capecitabine +oxaliplatin +50.4 Gy | ycT3N0 | 0 | 1 | Negative | Not required | None | None | 101 | Nodal, bone |
| 54/M | T3N+ | Capecitabine + 55 Gy | ycT3N0 | 2 | 3 | Negative | Performed | None | None | 9 | Liver |
APR abdominoperineal resection, cTN clinical tumor-nodal stage, LAR low anterior resection, LAR + IORT low anterior resection and intraoperative radiotherapy, LE local excision, nCRT neoadjuvant chemoradiotherapy, TME total mesorectal excision, TTLR time to local recurrence, TTDR time to distant recurrence, ypT post-neoadjuvant chemoradiotherapy pathological tumor stage