Table 3.
Values for sensitivity, specificity, PPV, NPV, and Youden index of the predicted probability at different cut-off values
| Predicted probability | Training cohorts | Validation cohorts | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Index | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Index | |
| 0.126 | 98.8 | 13.3 | 75.2 | 80.0 | 12.1 | 97.4 | 0.0 | 77.6 | 0.0 | − 2.6 |
| 0.228 | 98.8 | 20.0 | 76.7 | 85.7 | 18.8 | 97.4 | 9.1 | 79.2 | 50.0 | 6.5 |
| 0.315 | 97.5 | 26.7 | 78.0 | 80.0 | 24.2 | 94.9 | 18.2 | 80.4 | 50.0 | 13.1 |
| 0.465 | 96.3 | 43.3 | 81.9 | 81.3 | 39.6 | 89.7 | 36.4 | 83.3 | 50.0 | 26.1 |
| 0.513 | 96.3 | 46.7 | 82.8 | 82.4 | 42.9 | 89.7 | 45.5 | 85.4 | 55.6 | 35.2 |
| 0.608 | 93.8 | 53.3 | 84.3 | 76.2 | 47.1 | 84.6 | 45.5 | 84.6 | 45.5 | 30.1 |
| 0.646 | 80.0 | 73.3 | 88.9 | 57.9 | 53.3 | 69.2 | 81.8 | 93.1 | 42.9 | 51.0 |
| 0.707 | 77.5 | 73.3 | 88.6 | 55.0 | 50.8 | 66.7 | 81.8 | 92.9 | 40.9 | 48.5 |
| 0.896 | 50.0 | 96.7 | 97.6 | 42.0 | 46.7 | 41.0 | 90.9 | 94.1 | 30.3 | 31.9 |
PPV positive predictive value, NPV negative predictive value, Index Youden index