Table 2.
The distribution of the immunohistochemistry scores
| Group 1 | Group 2 | |||
|---|---|---|---|---|
| Tumor markers | γpCR (n = 21) |
Non-γpCR (n = 75) |
γpCR (n = 9) |
Non-γpCR (n = 34) |
| HER2 | ||||
| Negative | 19 (90%) | 57 (76%) | 8 (89%) | 26 (76%) |
| Positive | 1 (5%) | 17 (23%) | 0 (0%) | 8 (24%) |
| Missing | 1 (5%) | 1 (1%) | 1 (11%) | 0 (0%) |
| HIF1αnucleus | ||||
| Negative | 8 (89%) | 31 (91%) | ||
| Positive | 1 (11%) | 3 (9%) | ||
| HIF1αcytosol | ||||
| Negative | 2 (22%) | 13 (38%) | ||
| Positive | 7 (78%) | 21 (62%) | ||
| PTCH1 | ||||
| Negative | 2 (22%) | 4 (12%) | ||
| Positive | 7 (78%) | 30 (88%) | ||
| CD44 | ||||
| Negative | 1 (11%) | 15 (44%) | ||
| Positive | 8 (89%) | 19 (56%) | ||
| SHH | ||||
| Negative | 0 (0%) | 3 (9%) | ||
| Positive | 9 (100%) | 31 (91%) | ||
Abbreviations: γpCR, pathologic complete response; HER2, human epidermal growth factor receptor 2; CD44, cluster of differentiation 44; HIF1α, hypoxia-inducible factor alpha; PTCH1, protein patched homolog 1; SHH, Sonic Hedgehog