Table 3.

Antihyaluronidase activity of the extracts obtained from the mycelial cultures of Ganoderma applanatum, Laetiporus sulphureus, and Trametes versicolor

Concentration [µg/mL]	Inhibition of hyaluronidase activity (%)
	Ganoderma applanatum	Laetiporus sulphureus	Trametes versicolor	Positive control
3000	1.56 ± 1.02***	97.76 ± 1,27 ns	24.28 ± 0.63***	96.57 ± 1.33
2000	0.67 ± 0.67***	93.50 ± 0.36 ns	16.67 ± 0.49***	95.27 ± 1.39
1000	0.23 ± 0.39***	87.76 ± 6.49 ns	6.99 ± 0.70***	91.11 ± 1.50
700	0.00 ± 0.00***	34.18 ± 2.90***	2.86 ± 0.45***	80.56 ± 0.75
500	0.00 ± 0.00***	6.22 ± 0.77***	2.17 ± 1.92***	38.84 ± 1.33
300	0.00 ± 0.00***	2.55 ± 1.10***	0.00 ± 0.00***	21.86 ± 4.04
200	0.00 ± 0.00***	0.43 ± 0.75***	0.00 ± 0.00***	13.86 ± 2.70
100	0.00 ± 0.00*	0.00 ± 0.00*	0.00 ± 0.00*	4.39 ± 0.88
0	0.00 ± 0.00 ns	0.00 ± 0.00 ns	0.00 ± 0.00 ns	0.00 ± 0.00
IC50 [µg/mL]	> 3000	760.01	> 3000	509.79

Positive control: quercetin (dihydrate)

Data are presented as the mean ± SD (standard deviation); n = 3 repetitions. Anova test was used to reveal the differences between paired groups of elements in rows

*Differences statistically significant for p < 0.05 vs. positive control

**Differences statistically significant for p < 0.01 vs. positive control

***Differences statistically significant for p < 0.001 vs. positive control

ns not statistically significant

(Statsoft STATISTICA)